Knowledge Area – Maison MGA Internal Publications

Characterization of a pharmaceutical lentiviral vector by orthogonal particle analysis techniques

Lentiviral vector (LVV) products are used to generate therapeutic chimeric antigen receptor (CAR) T cells.

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Characterisation of extracellular vesicles directly in diluted canine and human blood and plasma for therapeutic plasma.

Technology Evaluation: Quicker way of Lentiviral Vector Physical Titer Determination

The measure of HIV-1 p24 antigen by ELISA is a well-established method for lentivirus quantitation.

Rapid characterization of human viruses in a droplet using Interferometric Light Microscopy (ILM) in a BSL3

Preliminary results show that ILM is not able to distinguish HIV-1 from viral particles derived from HIV-1...

Rapid Characterisation Of Phage Suspensions By Interferometry

Phage production’s downstream process includes a critical purification step susceptible to destabilise phage suspensions.

Videodrop : for a fast characterization of Extracellular Vesicles following a standard protocol

Maximizing MSC-EV Yield with Preserved Quality Using a Xeno-Free and Defined Formulation

Human mesenchymal stem cells (hMSCs) have strong therapeutic potential due to their self-renewal and multi-lineage differentiation abilities.

IXAKA’s versatile platform for the bioproduction & characterization of lentiviral vectors

Fast and easy characterization of diverse viruses using Interferometric Light Microscopy (ILM)

Videodrop (ILM) is a custom microscope that uses interference phenomenon to detect the light scattered by individual nanoparticles in solution.

Validation of an Analytical Method for Lentivirus Physical Concentration Using Videodrop (ILM) following ICH Q2 Guidelines

Lentiviral vector (LV) clinical application involves large-scale Good Manufacturing Practice (GMP), including production purification and quality controls. By rapidly measuring the size and physical titer of nanoparticles in solution, Videodrop can be integrated in lentiviral quality control strategy.

Assessing the particle concentration of mRNA-LNP using VIDEODROP: A new metric for LNP manufacturing, optimization & standardization

Videodrop is an innovative nanoscale imaging technology. Based on the principle of interferometry, Videodrop makes it possible to measure the size and concentration of nanoparticles

A straightforward solution for transfection complexes size kinetics follow-up

Transfection efficiency remains a crucial hurdle in viral vector production (LV or AAV) using transfection reagent-based methods.