AdvantaFlex® Tube Sealer

AdvantaFlex® tubes are widely used in the production of vaccines, bioreactor processes, filtration, high-purity water transfer, pharmaceutical distribution and sampling systems. These tubes are suitable for pharmaceutical, laboratory and biotechnological applications. If the fluid to be transferred must be replaced during the process, it is necessary to separate the two devices attached by the tubing. To do this, it is essential to disconnect the tube by using a specific machine. This is the tube sealer that can guarantee aseptic disconnection of AdvantaFlex® tubing.


Operation of the AdvantaFlex® Tube Sealer

Using a sealer is a safe way to separate AdvantaFlex® tubes without risk of contamination. With the help of this device, any proliferation of germs is ruled out. As these are perfectly weldable and heat-sealable pipes, the use of the disconnector is the best solution.

AdvantaFlex® tubes are dedicated to transferring sensitive fluids, so the use of the disconnector in clean rooms is mandatory. Thanks to thermo-sealing at the time of disconnection, microorganisms that may develop in the tubes will be destroyed. It also eliminates any risk of fluid leakage from the tubing.

The disconnector has clamps between which the tube that is to be disconnected is inserted. The device incorporates an electromagnet that locks the clamps when closing. The disconnection cycle is then initiated by the operator. A disconnection cycle has two phases:

  • In the first phase, the temperature level of the clamps is increased by a heating device until it slightly exceeds the melting point of the tubing.
  • In the second phase, the temperature level is maintained to ensure the fusion of the tube and eliminate any germs that may have been present between the tube and the clamps.

The vane pump integrated in the device reduces the melting temperature until it is safe for the operator.

The electromagnet then unlocks the clamps to release the tube. The operator examines the fusion process and cuts the tube with a simple pair of scissors.

Technical Characteristics of the MGA Technologies Tube Sealer


The sealer ensures aseptic disconnection of sterilized AdvantaFlex® tubes. In order for the device to support various formats, anodized aluminium clamp sets are included. The tube disconnector does not require compressed air and works by simply connecting it to the 110V and 220/230V – 50/60 Hz mains supply. The device is compatible with tubes of 1/4″, 3/4″, 1/2″ and 3/4″ in diameter.

MGA Technologies is a Lyon-based company that designs and manufactures the AdvantaFlex® tube Sealer. Specialized in the production of custom-made machines for various sectors: aeronautics, precision mechanics, agri-food and automotive, MGA Technologies creates and manufactures various types of special equipment for professionals in the pharmaceutical, medical and biotech industries. The company provides support to its customers throughout their projects.

A contact form is available on the company’s website if you wish to purchase the AdvantaFlex® tube disconnector. Their expert team will be able to provide you with all the information you need about the device.

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Contact our commercial team to get a customized quote for a AdvantaFlex® Tube Sealer by MGA Technologies.